To adjust for possible confounding, it is common to match on other variables as well. We say that the controls are matched on study time. In a nested case-control study, controls are selected for each case from the individuals who are at risk at the time at which the case occurs. Nested case-control studies: should one break the matching? Analysis that accounted for matching was performed in only 52% of the case-control studies. Of these 23 matched case-control studies, 12 (52%) justified the use of matching, and 9 (39%) noted the strengths or limitations of this approach. Matched variables differed substantially across studies. Of 57 case-control studies of antimicrobial resistance, matching was used in 23 (40%). Role of matching in case-control studies of antimicrobial resistance.Ĭerceo, Elizabeth Lautenbach, Ebbing Linkin, Darren R Bilker, Warren B Lee, Ingi
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